The Gauteng province of South Africa reported 19 new cases of cholera in Hammanskraal on Sunday, with 10 deaths.
After the disease had spread from Malawi into South Africa, the country reported its first cholera death in February.
The total number of cases in South Africa was unknown as of Sunday, but the province of Gauteng, which includes the cities of Johannesburg and Pretoria, has been hit the hardest.
Cholera is primarily transmitted through the consumption of contaminated food or water, and it can cause severe diarrhea, vomiting, and weakness. Death can occur within hours if not treated.
Around 12,000 cases were reported in South Africa in 2008/2009, following an outbreak in neighboring Zimbabwe that caused a surge in imported cases and subsequent local transmission.